Innovator Awards for Postinfectious & Posthemorrhagic Hydrocephalus
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The Hydrocephalus Association is soliciting applications for research on postinfectious and posthemorrhagic hydrocephalus. The goal of this initiative is to provide seed funding for bold and innovative research with the potential to transform the field of hydrocephalus through the understanding of disease mechanisms and the development of novel therapies and treatment approaches.
Postinfectious Hydrocephalus Focus Area:
- The award provides short term seed funding for up to 12 months.
- Proposals may be submitted for actual costs at one of two funding levels, $25,000 or $50,000.
- Total funding is expected to be $200,000.
This award is intended to fund innovative research in postinfectious hydrocephalus, including both pediatric and adult onset postinfectious hydrocephalus. Topic focus areas include identification and/or improved understanding of the primary and secondary mechanisms leading to the development and progression of postinfectious hydrocephalus and identification and/or testing of novel therapies and treatment approaches for postinfectious hydrocephalus. Priority will be given to applications testing new theories, using innovative approaches, and/or applications with clear therapeutic implications. Support for the development of new animal, ex vivo, or in vitro models of postinfectious hydrocephalus will be considered. All applicants intending to include human subjects must indicate this in the LOI and will be contacted to determine if the project falls within the scope of this RFA. Human imaging studies that do not test a specific, mechanistically driven hypothesis will not be considered. This award is not intended to support the development of medical devices, instrumentation or other commercial applications.
Posthemorrhagic Hydrocephalus Focus Area:
- The award provides short term seed funding for up to 12 months.
- Proposals may be submitted for actual costs at one of two funding levels, $25,000 or $50,000.
- Total funding is expected to be $200,000.
This award is intended to fund innovative research in posthemorrhagic hydrocephalus, including both pediatric and adult onset posthemorrhagic hydrocephalus. Topic focus areas include identification and/or improved understanding of the primary and secondary mechanisms leading to the development and progression of posthemorrhagic hydrocephalus and identification and/or testing of novel therapies and treatment approaches for posthemorrhagic hydrocephalus. Priority will be given to applications testing new theories, using innovative approaches, and/or applications with clear therapeutic implications. All applicants intending to include human subjects must indicate this in the LOI and will be contacted to determine if the project falls within the scope of this RFA. Human imaging studies that do not test a specific, mechanistically driven hypothesis will not be considered. This award is not intended to support the development of medical devices, instrumentation or other commercial applications, nor is it intended to support the development of new animal, ex vivo, or in vitro models of hydrocephalus for the purpose of future research.
The number of awards made will depend on the quality of the applications received and the research priorities determined by the Hydrocephalus Association. The Hydrocephalus Association will accept applications from researchers based at accredited non-profit research and academic institutions throughout the world. The award provides no institutional overhead. All applications must be submitted in English. In upcoming years, the Hydrocephalus Association anticipates a follow-on RFA for multiyear support.
Eligibility Criteria
To be eligible, candidates must:
- Have a publication record containing articles that are innovative and high impact
- Have demonstrated the ability to independently supervise staff and research
- Have completed one or more of the following degrees: MD, PhD, DSc, DO, Pharm.D, or equivalent
- Hold a research associate, assistant professorship, associate professorship, professorship, or any equivalent academic or non-academic position
PLEASE NOTE
Applicants must be members of the Hydrocephalus Association’s Network for Discovery Science. To create a HANDS account, please visit: http://hands.hydroassoc.org/.
Application Details
The Letter of Intent (LOI) components include:
Click HERE for LOI form
*All applicants that intend to include human subjects will be contacted to determine if the project falls within the scope of the RFA.
- A one-page summary of the project*
- Identification of the supporting institution
- Identification of three potential reviewers
The Full Application components include:
- Contact details and other relevant administrative information (Face Page)
- Proposal Budget (Budget)
- Biographical sketches are required for the Applicant, Co-Investigator (if applicable), and Key Personnel. Biographical Sketches should not to exceed five (5) pages (BioSketch)
- A research plan for the proposed project, of not more than six (6) pages, that contains a summary, specific aims and hypotheses, background and significance, research design and methods, and next steps (5 pages), and literature cited (1 page). (Research Plan)
- A description of the institutional facilities and any consultations/collaborations if applicable. (Facilities and Collaborations)
- Applications from all candidates should also include a letter from the appropriate administrative institutional official confirming the institutions commitment to the responsible conduct of research, the candidate’s eligibility and good standing, and that, if selected, the candidate would be able to accept the award.
All applicants must provide assurance of compliance with local research regulatory bodies and with local laws in advance of the award start date. Additionally, for applications using human embryonic stem cells or human tissue the candidate must obtain appropriate Embryonic Stem Cell Research Oversight Committee (ESCRO) and human subjects research approvals in advance of the award start date.
All applicants must submit an LOI. LOIs must be submitted to research-loi@hydroassoc.org before 5:00 PM (Eastern) on February 23, 2017. LOI decisions and invitations to submit full proposals will be made in late-February. Full applications are due before 5:00 PM (Eastern) on April 11, 2017. Grant finalists will be contacted in May 2017 and announced in May 2017. For additional information, please contact Jenna Koschnitzky, PhD at research@hydroassoc.org or 240.483.4540.